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Cystic fibrosis in children: symptoms you need to knowOne in 2,500 newborns is born with cystic fibrosis. Cystic fibrosis in children is a serious congenital genetic disease. How does it manifest itself and what is its course? How to recognize and treat her? You will learn from the article below.
Cystic fibrosis - a genetic disease
Cystic fibrosis is one of the most common genetic diseases in humans. It is estimated that every 25 person carries his or her gene, but most have no idea about it. There are at least 1500 gene mutations responsible for the disease.
If both the mother and father of the child are carriers of the defective gene, the child will most likely be born sick. Cystic fibrosis in children occurs in both boys and girls. Is a congenital disease.
The disease involves malfunction of the glands and the presence of thick secretions, forming mucous plugs in the respiratory, digestive and reproductive systems. The symptom is disturbed electrolyte transport, dense, adhesive secretions in the bronchi. The consequence, however chronic inflammation caused by bacterial growth and irreversible lung damage. The problem is that mucus blocks important substances necessary for digestion, as a result of which digestion is not effective, nutritional deficiencies occur and growth inhibits.
How is cystic fibrosis diagnosed?
Cystic fibrosis can already be recognized in early pregnancy, between 8 and 12 weeks of pregnancy. Unfortunately, a negative result cannot guarantee that your child will not be ill. The pregnancy test detects a maximum of 70 mutations, and cystic fibrosis is diagnosed in 1300.
You can also do genetic test, which allows you to detect the most common gene mutation responsible for the emergence of the disease. The study allows you to assess the risk of having a child with CF.
Currently in Poland (from June 1, 2009) all newborns are screened for cystic fibrosis (blood sampling on special paper. During one test, cystic fibrosis and phenylketonuria diagnostics are performed). Only parents whose children are at risk because of a result exceeding the norm receive the test results. The results should arrive before the child is 3 weeks old. If the results are correct, parents do not receive any messages. Thanks to screening tests, it is much faster to diagnose the disease (although the examination of newborns, unfortunately, does not give 100% certainty). Prior to mandatory testing, the average age at diagnosing cystic fibrosis was 3.5-5 years. Early diagnosis gives the chance for a long life.
The sooner the disease is diagnosed, the greater the chance for the child's proper development. Children who have not had an examination in the neonatal period or those who have disturbing symptoms can be performed sweat test, which involves determining the concentration of sweat chloride. The test should be performed twice.
Cystic fibrosis in children: symptoms
Degree of severity of CF symptoms depends on the type of gene mutation, which is necessary for the development of the disease. Cystic fibrosis may have classical or atypical course. Symptoms most often appear right after birth or in early childhood, only in a few situations do symptoms develop during adolescence or adulthood.
The disease can be mild or severe. Symptoms may affect several systems or only one organ. The most common are:
- changes in the respiratory system: formation of sticky, difficult to remove secretions,
- paroxysmal wet cough of a chronic nature,
- recurrent pneumonia and bronchitis,
- very salty sweat of a child,
- obstructive pneumonia,
- breathing difficulties,
- loud breath with wheezing,
- polyps in the nose
- chronic sinusitis
- problems with the pancreas - diabetes and glucose intolerance.
- stomach pain, bloating, diarrhea or constipation
- foul-smelling, abundant stools.
- lack of meconium excretion - one of the first and more important symptoms of newborn cystic fibrosis, it can affect up to 20% of children with cystic fibrosis,
- bloated stomach,
- profuse vomiting
- slow growing
- insufficient weight gain,
- prolonged neonatal jaundice,
How is cystic fibrosis treated?
The fight against cystic fibrosis is long and difficult. Cystic fibrosis is a chronic disease that requires constant medical supervision and during periods of exacerbation of hospitalization. Many respiratory infections usually end with antibiotics.
Unfortunately, a complete cure for cystic fibrosis is not possible. However, medicine is developing so quickly that it cannot be ruled out that new treatments for cystic fibrosis will arise.
Cystic fibrosis in children is treated by administering lliquefying secretions in the bronchi. In addition, in the event of problems with the pancreas, the sick person must take enzymes and vitamin preparations that support digestion.
Inhalations and drainages are also performed more and more often.
The most important thing about cystic fibrosis treatment is early diagnosis. Untreated disease leads to death.
During pregnancy, many autoimmune cancers, such as multiple sclerosis or ocular inflammation (uveitis), disappear or significantly improve. A recent study provides an explanation of this phenomenon.During pregnancy, the cells of the immune system have decreased activity of the enzyme pyruvate kinase, read in a study by Howard R. Petty and Roberto Romero, published in the American Journal of Reproductive Immunology.
A normally functioning immune response depends on a compound called pyruvate, potentiating the potentiation of calcium-regulated molecular processes. The newly discovered mechanism represents a new path that may be the target of practitioners.
"It may result in the development of new drugs that gently regulate pyruvate kinase activity, altering immune function during pregnancy," Petty said. Thus, in addition to pre-eclampsia, rheumatoid arthritis, type I diabetes, and uveitis may be treated with similar types of drugs. According to Petty, this is a metabolic process that has two characteristics. It reduces the normal immune function so that the fetus containing the paternal white is not ejected, but at the same time it must support the growth of the fetus's cells.
The activity of pyruvate kinase and its results in both functioning of pyruvate enhances cell growth while altering immune function. Following pyruvate kinase activity during inhibited pregnancy, cellular metabolism is increased, leading to increased production of fats, carbohydrates, amino acids, and other substances that are indispensable for cell growth. Calcium enhances the production of the intermediate molecule called cytokines. When pyruvate levels are reduced in pregnancy, the calcium-mediated signal is also decreased, so that immune function changes in a condition other than pregnancy.
"By interfering with the mechanism above, we can keep pregnant immune responses, but at a level that still doesn't block the fetus," Petty explained.
The study included 21 pregnant women in the third trimester, 25 preeclampsia women and a non-pregnant control group. Higher enzyme levels in preeclampsia women support the theory. Preeclampsia is similar to inflammatory diseases. Without reducing pyruvate levels, inflammatory diseases become more severe. According to Petty, in the future we could measure the levels of these enzymes in early pregnancy, suppressing pre-eclampsia and other events, and we will be able to cure them with new drugs.
Planning to become pregnant or approaching the end of pregnancy
One of the most basic questions in mind of expectant mothers
whether they receive financial support. According to the law, every member of SSI
the mother can get paid leave before and after the birth. However, at the same time
increased costs with the baby's birth to the parents' eyes
The infant's arrival to the world is as material as the moral responsibilities
also brings responsibilities. The change in your life is only at the level of emotion
not in your lifestyle. More issues to think about now, worry
the more you do and the more you worry. With your baby,
being happy and healthy is of course worth everything but you can't deny
The facts are right under your nose. Choosing your baby's name, preparing the room,
planning your future is as enjoyable as it is necessary. And these plans come to life.
There is a passing part. This part is the most suggestive part of the parents
can not hesitate to say. Suddenly increased especially after birth
you need to be ready for costs to change your life.
So after birth
of paid money so that the amount of top
Tactics. This support was provided to civil servant mothers, while other employees
not provided. Officer mothers receive postpartum payment while other moms work
can receive disability allowance. Birth
post paid money monthly coefficient *
When calculating the SSI mothers prenatal
and then calculated over the period of leave.
The details of the article as follows:
The second paragraph of Article 16 of the Law and the 4th
(b) with the muhtars mentioned in paragraph (a) and (b) of the first paragraph of
and (1), (2) and (4),
Article (a) and (g) of the article insured women, maternity
temporary temporary incapacity allowance will be provided. Temporary
incapacity allowance, depending on the doctor's rest
and in the next 8 weeks, in the case of multiple pregnancy,
2-week period will be added to the period will be paid for each day.
With the request of the insured woman and the approval of the physician
rest period after birth
It will be added. To add these periods up to 3 weeks before birth
health report authorized by the health service
The dragon disguise
- Glue the two balloons together with adhesive plaster.
If we spend time with a child
There are many reasons to move. We can go smaller and cheaper, bigger and nicer - unfortunately, one thing is for sure: we see a lot of nervous people. Fortunately, smart design can help reduce the pain of the hunger a bit.
Before leaving: the author's biggest and smallest child
Moving for a child is quite different from the eyes of an adult. Dad and mom are really nervous about rational things: how can they pack up on time, how difficult it will be to get the furniture upstairs, whether they will put all the stuff in their new home, when they will have a connection, with no time Emotional Losses autopsy.But with the eyes of a kid, moving is nothing short of astonishing a series of painful farewells. We would think that a child is a flexible mind: family is the most important relationship, and no matter where we sleep, we live. However, it is worth paying attention to what the little one feels, even if he does not speak roulette. If you are well prepared and given time to get used to the idea of change, your pain will be much less.When is it worth telling him? The sooner, the better! Let's get him involved in the design phase, tell him why he needs to move, and let him know that this will make the whole family happy. Encourage her to feel free to express her feelings, and share her feelings with her so that she is free to express her feelings. There are three main stages of migration: a kйszьlхdйs, the move day And a letelepedйs idхszaka. It is worthwhile to actively involve the child in all of them.
Get ready!At the time of preparation, the most important thing is to make the child aware that change is very good. For this, feel free to maximize the kid-friendly benefits of a new place: the garden, being close to the park, getting an outside room, or having a large kitchen can have breakfast for the whole family; at the same time, emphatically assert that old good things are moving from life to the new place: your old bed, your toys, your beloved poster on the wall, the little books you usually eat. It is very important for your child to pack his stuff carefully, label it, and keep every single piece of it. Bar move is great when you move, oppose him and don't start sorting your stuff now.If you really want to get rid of some stuff, and you think you might not get it, don't throw away all that stuff. A good way to do this is to pack it in the box you want to throw away and not to unpack it in the new house. If your child is not looking for it in half a year, it can be thrown away, but if you were to miss it, you can take it out of the chamber.
Move in together!Friends and relatives often offer help with taking the child for a couple of days instead of packing and shoeing. At first glance, it may seem like a good idea to get rid of a little bit of chaos at the time of coming home to a new, nicely furnished home, but after school, this is not a fortunate choice. The effect is a sudden change causes a very strong loss in your child, it is scary to know that you suddenly lose the most important, stable point in your life: your home.Serious anxiety can develop in him and he may not want to leave home or breast for months, he didn't see. If it is possible, it is more fortunate to ask a friendly friend to come over and take care of the baby while moving. Moving exciting adventure for the child to experience a change of state and wonder about the changing nature of things. His statue, which suddenly turns out and looks much larger, is a new home that is slowly filling up with home stuff. The point is that today we eat dinner at the house because of the lack of dishes and how strange it is to go to the new toilet. needs to be done. Moving day is really hard work for everyone and a little kid can be very much under foot. If you feel like it, you don't have the energy to listen to it, try to spend as little time as possible, and try to take the time to say goodbye to your old home, and welcome the new one as soon as possible.
Say goodbye slowly!If you are moving far, you may think you have no reason to go back to your old home. A little playthrough isn't worth living in the car, others live in the apartment, it's crazy to look in their windows at how they live. It can also annoy the child, because in vain, we cannot turn the wheel of time back, we cannot go back. It is very likely that many children will react very violently when returning to old places. You may think she will be crying, sad - but these feelings need not be feared. THE nostalgia good thing it will calm down soon and it will be easier to accept the new place if you make sure that the old one has not disappeared. I got it, it just changed. And the change is good. You'll be welcomed at the old grocery store, your neighbor will definitely let you in, and maybe the old ladies will allow you to peek in. Yes, things have changed. But if you give it some time, you will soon hear that he is happy to tell you what it is like to live in a new place. And as the weeks and months pass, the new home slowly builds. Soon everything will be full of toys, welcoming you to the new shop, and when you whip it on the freshly painted wall, don't yell, just smile, because it means you're finally here at home.
You can get rid of abdominal fat with this oil
When it comes to dieting, we all have ideas about how much we want to give up. What a pity our body somehow never pays attention to it and diets just don't succeed as planned!
You can get rid of abdominal fat with this oilThere seems to be something that can help us specifically in our fight against grease. According to health researchers, the colza oil Introducing a diet into our diet can help to overcome the weight that is deposited on our stomachs, while it is also very healthy. Penny M. Kris-Etherton, according to a distinguished professor of nutrition, rapeseed oil monounsaturated fatty acids because of its ability to reduce the amount of malignant fats that we have, and its beneficial effect, according to the results of our research so far, is specifically focused on the levels of fat that are loaded in the abdominal area. All subjects had at least one of the symptoms that predispose to metabolic syndrome: high blood pressure, type 2 diabetes or high blood sugar, low HDL-cholesterol (high cholesterol), and high blood pressure. The rйsztvevхk kцvettek a nйgy weeks set elхre йtrendet which normбl rapeseed oil, high zsнrsavtartalmъ rapeseed oil, high zsнrsavtartalmъ rapeseed oil hozzбadott omega-3 zsнrsavval, corn / sбfrбnyolajat or linseed / sбfrбnyolajat tartalmaztak.A vizsgбlt szemйlyek kйt, daily energiaszьksйgletьknek megfelelх kalуriatartalmъ smoothie So-called smoothies were consumed daily, containing orange ice cream, low fat milk, frozen strawberries and one of the oil tested. oil consumed by their colleagues.
Giving children space is necessary. This means giving them privacy, but also autonomy and independence, something basic for the proper development of children. The question is how much space, how to do it, when to do it and how to manage it. And it is that we must bear in mind that Giving children space does not mean letting them do whatever they want.
Children need your privacy and this tends to show itself especially during puberty and adolescence. It is in these stages that children can claim their space most intensely.
As children grow older, children's dependence on parents gradually disappears, or rather changes. It's not that they no longer need them, but that they don't need them for everything. They want to do things alone, they no longer demand everything from them, and this is good. It is a sign that they are autonomous and that they trust themselves, so giving them independence little by little is necessary.
And giving them a certain autonomy goes through giving them their own spaces. This does not mean letting them do what they want when they want. It is not about being permissive, but understanding with their needs, educating them both in responsibility and in knowing how to make decisions.
An age is coming when our children claim their own spaces and demand freedom. An example of this is their room, which they spend more and more time in it. They also ask us to keep our distance when they are with their friends. This is normal as they are entering a stage where their privacy is very valuable. And we must give it to him.
But children must also understand that there has to be some control; that there are certain rules, responsibilities and limits that they have to respect and to comply with. That is, the more responsible you show me that you are, the more space and more freedom I can give you.
Giving children space can be reflected in different areas of day-to-day life: from a physical space at home, to a virtual space on social or personal networks. We analyze each of them.
1. You have to leave their own space at home
First of all, we can leave their space at home. Your room is your space and also your responsibility. We will knock on the door when we go to enter, they must have the possibility to choose how they want to decorate it (we have all filled the walls with posters of our favorite artists), but they also have to know that it is their responsibility and they must commit, for example, to keep it in condition, (neat, clean ...)
2. Monitor its use on social networks
Something that now worries parents a lot is the use of technologies and social networks. On many occasions, parents do not know what their children are watching, who they are talking to, what networks they operate or how they work. Although they can make use of them, it will be the task of the parents to educate their children in the proper use of mobile phones, the internet and the networks, and to know what will happen if they are misused.
Here it is advisable that, for example, computers with internet access are in common places, establish parental controls, not give them their own mobile phone too soon ...
3. You always have to respect their privacy
You have to respect their privacy and, for example, avoid talking about their affairs in front of other people. We will have to try not to tell certain things in public that affect the privacy of our children and that may make them feel uncomfortable.
4. Let them make decisions
Giving them space also means letting them make their own decisions and choices, and teaching them to be responsible for their consequences.
As we said before, leaving them their space is not being permissive and letting them do what they want as they want. Giving them space is being understanding of their needs, is to educate them to be autonomous, responsible and independent. But always establishing clear limits and rules.
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